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What you said is almost like complaining that it's the man's fault that a women didn't get the job because the man does too good of a job. It's not up to the man to downplay his capabilities and fall on the sword of social justice, it's up to the woman to step up and convince people that she's just as capable.

It would be a better system if people didn't misrepresent themselves. That is how we end up with people getting misleveled and underperforming.

It's also what leads to bad managers and the kinds of issues everyone bemoans. The job shouldnt go tothe best self-promoter.

The fact that it works that way is a problem we should be trying to solve. Your problem is that youre using the term privilege to refer to individuals when its a term used to describe a population.

Sure those two hypothetical homeless people, the aboriginal one has access to more. Thats a singular situation that you created to justify your narrative.

When you look at the whole population you see that aboriginal people are far more likely to be homeless overall so they are, AS A GROUP, less privileged.

Hence the extra services to attempt to address this injustice. White people as an entire group have privilege. Pulling individuals out of the population to argue against privilege is like saying "its cold today, so much for global warming".

Stupid and missing the entire point. Let me be clear about this: I have no problem with speaking in generalistions about collectives.

My problem is when people argue from the general to the specific. A good example: The question is asked, "do black people commit more violent crime than white people?

However, is it therefore fair to argue that "since black people commit more violent crime than white people, the black guy in accounting is violent"?

If one person has objectively more access to resources than the other, how is the OTHER person privileged?

By that metric, if I quit my job and sit home all day shitposting on Reddit for a living, can I call my former workmates privileged because they still work, and still have income, and still have money and all the perks it brings?

Because even though we had the same opportunities, I made different choices that sucked for me in the long term?

That's seemingly what you're arguing. But not individual white people, so if you're going to examine the individual anyway, why bother with the collective?

Why bother saying "white people have privilege" if not all, not even most, white people are privileged? Are you sure it's not the other way around -- more like looking at a tiger cage in a zoo and saying "Using this cage as a sample size, the average tiger population of Earth is two tigers per fifty square metres"?

Overly specific sampling as you illustrated earlier cuts both ways. How do we know you're not the one saying "some white people are privileged, so much for equality"?

Just because a single person in the group isn't privileged, doesn't mean the others aren't. Think of it as a set of data. There's a set for white people ans a set for aboriginals.

Almost anything you plot becomes a bell curve. The white people bell curve it just shifted a bit higher. So you'll still have white people who are having a shit time, and you'll still have aboriginals whore having a great time.

But overall you see that white people are having a better time than aboriginals. Taking two points from the data doesn't prove or disprove that.

Its not a concept that should be applied at an individual level. Because sociological articles will justify their sample size. This doesnt just come from some special snowflake deciding white people suck.

Its been studied for near on 50 years. Anything that applies to "white people" must, by definition, apply to all white people. It's axiomatic.

Like saying, "white people have white skin". Are there white people who have African skin tones? There are none.

Because those are not, by definition, white people. I absolutely don't deny this and, as someone who grew up in the NT and lived there for 25 years, the discrepancy between white people and Indigenous people is vast.

However, what I don't accept is that this difference is due to special, subtle, unearned advantages that are almost impossible to quantify yet produce such vastly different results.

Small differences in how people are treated by society at large cannot, realistically, such large differences in outcome make.

As I said. I have no problems talking about group trends because trends among groups can be observed and should be. And yes, there is a pretty big gulf between white people and Indigenous persons by basically any metric these days.

However, in my experience, 'privilege' is almost always applied at an individual level rather than a group level. Applying it by race does exactly this.

The difference in privilege between two homeless people by their race is completely meaningless. With that case, you also see a geographical divide in results as well, suggesting poorer access to resources.

This article explains how cultural differences and the fact ethnic minorities are more likely to live in areas with better educational facilities like London, could explain the reason for poor white males to be doing the worst in the GCSEs.

But even then, we see an example of privilege. This report from the UK government found "Poor white boys do worse in schools but black and Asian Muslim young people, girls especially, do worse for jobs," and are "less likely to face social immobility".

You act like there are only two sets of privilege, but class privilege is a very real thing which you've ignored in your rush to dismiss privilege as a concept.

Also, in this comment you use a study about blind recruitment. However, you try to extend the results of a study done on public service to all careers, despite the authors of the article never intending for it to be read in that way.

Furthermore, the study focused on senior positions which considering a majority of senior public servants are male and thus more likely to have relevant experience , and was only in the context of being shortlisted for an interview and not the actual employment.

I mean, if we're just pointing out random studies, what do you think about blind auditions making it more likely for women to get into orchestras?

You're simplifying the discussion when there's a wide range of sociological factors in play. The most educated people per-capita in the United States are not whites.

They are Jews, Indians, and other ethnicity. Do they have privilege? Or is it only whites? If you look at the richest ethnicity, the most educated ethnicity, the ethnicity in jobs like finance, marketing, sales, stocks, self-employed, etc, the leading results are whites only by absolute numbers.

Not per-capita. Because maybe things are different and different fields have different kinds of biases and different kinds of sociological factors affect things in complex, nuanced ways we don't really understand because they are so complex, so hitting society with a hammer and saying "White males ALWAYS have unearned advantage over all other people, period!

Working class is a bit misleading, in fact white males are not the worst performing group It's actually female Black Caribbeans.

Those statistics only use eligibility for free school meals FSE , gender, and ethnicity. The study uses data that compares the level of attainment for disadvantaged eligible for FSE and non-disadvantaged.

Essentially the attainment gap is largest for Irish and white British teenagers whilst it has decreased dramatically over the past decade for other groups.

Just because they are performing poorly doesn't mean they aren't privileged in some way. The much smaller minorities tend to have stronger family aspirations and positive cultural attitudes to learning.

The idea behind white privilege is that in 'white countries', due to history, people may stigmatise 'non-whites'. Also non-whites collectively may be in worse economic conditions as a result of past unfair treatment.

The summation of the effects of the aforementioned is white privilege. What you are doing with the homeless white man example is trying akin to using macroeconomic analysis to explain microeconomics.

Would this count as an "unearned" advantage, aka privilege, or is that "earned"? By that logic, is not white people's general focus on education and school attendance an "earned" advantage?

What separates white people's advantages from theirs? And at some universities people stigmatise whites, including whole days where white people are not permitted to attend.

For example, Obama's daughters are, objectively, infinitely more privileged than almost any white person on the planet, save a small handful of people.

They have Secret Service protection for life so will never, ever be the victim of violent crime even if they instigate it for some reason and will never, ever fear for their personal safety.

Having "Lived at the White House for eight years with my father, President Barack Obama" on their resume will ensure they get into any college they apply for.

How is it they, also, benefit from Affirmative Action? How is it they are not considered 'privileged'? People look at white people as a whole and say: "You have unfair advantages".

They then correct this using individuals, even if it's unwarranted, because it is applied by race not by individual need. Which is why discussion of privilege is a stupid thing because it doesn't apply to all people.

Somehow, they are still privileged. I'm trying to show that the notion that 'white men are privileged' is simply not true for all white men.

In fact, it is not true for most white men. I'm not arguing for specific, artificial advantages be created and enforced for straight white men.

That's Affirmative Action and I dislike it. So why are we leaning so hard on the concept of privilege if we don't even really have decisive proof of it?

Is not privilege merely a theory that, as I've shown, certainly has huge holes in it? White privilege is saying that as a white person, you're likely to have certain benefits over a black person.

See: Driving while Black. It's not saying "All whites have it better than all blacks in all instances", because only a literal half wit would take it that way.

If all races have different kinds of privileges, and white privilege does not apply to all white people, and all races and colours have different kinds of privilege that apply at different times and in different contexts then Why the focus on something that doesn't apply to all whites, and when it does apply, does not apply to all contexts and in all circumstances?

Surely you can concede when it comes to things like Affirmative Action there is a distinct disadvantage to being white and straight and male.

So in that context, is there "black privilege"? Well, if you're going to be like that, please stick to whatever your job is and stop commenting on Priviledge starts from the richest person on earth and ends with the poorest.

It is everywhere and really means nothing. Completely subjective. It means a lot unless you've lived with privilege your whole life and can't identify it.

Its subjective because how are you going to establish a rank system based on a bunch of complicated and interconnected metrics? The Cambodian earning 50 usd a month had priviledge compared to the other one who is earning 25 usd a month.

But hey what about the other one who is earning 10 usd a month? Then theres another guy earning 15 usd a month BUT in a warzone. Oh wait he has all his limbs.

What about that other guy who lost his arm - no he does not live in a warzone. Well at least he is not going to die of childhood lymphoma.

Its just another weapon of guilt for people to manipulate other people or to win internet arguments with. Some people think we live in a meritocracy and that white dudes like Dutton are just really talented.

Holy fuck, this is the longest "but mum, he started it! Is Dutton a racist dickhole for targetting specific help to these people?

Yeah, it;s pretty on the nose. But this shit that these farmers deserve the treatment they are copping because of the actions of people who shared the same skin colour can go fuck off and die.

Switch the skin colour and these people would be screaming bloody murder about genocide and white supremacy. Here's the thing; the majority of the Rohingya have left Myanmar and are now living in Bangladesh, who will not issue them an exit visa.

We could literally, as a nation, have an open borders policy towards Rohingya and we would get a tiny trickle in terms of people. But for the white South Africans?

Well, if we did that we would have huge numbers coming over. Many have left already. The percentage of patients reporting minor hypoglycemic episodes during the week treatment period was lower in the liraglutide-added group than in the insulin-increasing group The incidence of adverse events was higher in the liraglutide-added group than in the insulin-increasing group As expected with GLP-1 receptor agonists, gastrointestinal adverse events were most commonly reported in the liraglutide-added group, including nausea, vomiting, constipation, and diarrhea.

These events were mostly mild-to-moderate in severity and typically resolved after the first 4—8 weeks. There were no patients withdrawn from the 12 week study as a result of medication related adverse events in the two groups.

Compared with increasing the insulin dose therapy, the present study demonstrated the beneficial effects of adding the long-acting GLP-1 analog liraglutide to established insulin therapy, which resulted in a significant improvement in glycemic control, reduction in insulin requirement, lower incidence of hypoglycemia events and weight loss in the Chinese patients with poorly controlled T2D and abdominal obesity.

Although beneficial effects of combination use of GLP-1 receptor agonists liraglutide or exenatide and insulin were observed in previous small studies [ 17 — 19 ], most of these are retrospective studies.

This study is the first designed study using the insulin dose-increasing approach as an active comparator. The data from all six LEAD trials have been analysed in pooled meta-analysis which has shown that addition of liraglutide to existing OAD therapy resulted in mean HbA1c reductions of approximately 1.

In the present study, addition of liraglutide to the established insulin therapy resulted in a significant 1.

In this study, we also found that liraglutide-added treatment improved postprandial glucose control better than insulin-uptitration.

One possible explanation for this beneficial effect is that liraglutide can suppress glucagon secretion in addition to increasing the physiological insulin secretion [ 7 , 8 ].

Furthermore, add-on liraglutide treated patients had lower rate of hypoglycemic events and greater insulin and OAD discontinuation than did patients treated with increased insulin doses.

This suggests that the addition of liraglutide to insulin therapy might be a good practice to attain glucose control.

In the Diabetes Control and Complications Trial, subjects assigned to intensive therapy experienced a three-fold increased risk of severe hypoglycemic events [ 21 ].

A similar finding was also obtained in the UK Prospective Diabetes Study [ 22 ]. In the present study, no severe hypoglycemia events were reported in liraglutide-added group, while two patients in the insulin-increasing group reported severe hypoglycemia.

In addition, the percentage of patients reporting minor hypoglycemic episodes during the week treatment period was significantly lower in the liraglutide-added group than in the insulin-increasing group.

The finding is consistent with the previous studies [ 3 , 10 — 13 ] and highlights a second advantage to the liraglutide adding strategy.

The lower risk of hypoglycemia with liraglutide administration may be explained by its stimulation of insulin release and glucagon suppression in a glucose-dependent manner [ 23 ].

Obese patients with T2D are at high risk for CVD [ 4 ]. Given that recent studies have shown an association between hypoglycemic events and risk cardiovascular events [ 24 ], our study may suggest that adding liraglutide to insulin is advantageous from a cardiovascular standpoint owing to its reduced frequency of hypoglycemia compared to treatment with insulin only.

In addition to a lower risk of hypoglycemia, liraglutide may favorably affect several CV risk factors, such as blood pressure, lipid profiles, and body weight [ 11 — 17 , 25 ].

A recent meta-analysis of cardiovascular safety by exenatide showed that patients treated with exenatide twice daily were less likely to have a CVD event than were treated with other glucose-lowering therapies [ 26 ].

The direct cardiovascular benefits of adding liraglutide should be verified in prospective clinical trials.

Insulin, the most effective therapeutic agent for lowering the blood glucose, is particularly associated with weight gain [ 27 , 28 ] and especially causes undesirable weight gain in an already obese population.

All OADs for the treatment of T2D are associated with either weight gain or weight neutrality, except for GLP-1 receptor agonist class which resulted in weight loss through central appetite suppression, leading to reduced energy intake.

Therefore, the third advantage to the liraglutide adding strategy was the reduction of body weight. In the present study, a mean weight reduction of 5.

It is greater than that observed in any of the preclinical trials of liraglutide as monotherapy or as add-on therapy to oral agents [ 10 — 13 ] and the trial performed in Asian countries [ 3 , 29 ].

As seen in a recent observational study which combined liraglutide and insulin therapy, the weight loss seen in our study may be explained by a combination of reduced caloric intake caused by the appetite-suppressing effect of liraglutide coupled to reduced lipogenesis achieved by insulin reduction [ 18 ].

Moreover, the mean waist circumference reduction of 5. Therefore, mean 5. Participants who are T2D and abdominal obesity are likely to develop hypertension, hypercholesterolaemia, liver disease and eventually CVD.

Accordingly these participants have a considerably elevated risk of morbidity and mortality. Unfortunately, traditional treatments for these patients are associated with weight gain and hypoglycemia that limit the number of patients reaching acceptable therapeutic goals.

The present study provides evidence that liraglutide, when given to insulin-treated obese patients with T2D, results in clinically relevant beneficial effects on body weight and waist circumference reduction, lower risk of hypoglycemia and insulin dose reduction in addition to improved glycemic control.

In conclusion, adding liraglutide to insulin therapy provides a better chance of achieving good glycemic control with a lower daily insulin dose and fewer hypoglycemic events compared to increasing insulin dose.

This regimen also resulted in a significant reduction in body weight and waist circumference, suggesting that the addition liraglutide to insulin treatment in obese patients with T2D maybe a more effective option than increasing the insulin dose alone.

Larger randomized, prospective studies are required to define the best practices for combination therapy with insulin and liraglutide and to evaluate its long-term cardiovascular effects.

Hossain P, Kawar B, El Nahas M: Obesity and diabetes in the developing world-a growing challenge. N Engl J Med. Chan JC, Malik V, Jia W, Kadowaki T, Yajnik CS, Yoon KH, Hu FB: Diabetes in Asia: epidemiology, risk factors, and pathophysiology.

Yang W, Chen L, Ji Q, Liu X, Ma J, Tandon N, Bhattacharyya A, Kumar A, Kim KW, Yoon KH, Bech OM, Zychma M: Liraglutide provides similar glycaemic control as glimepiride both in combination with metformin and reduces body weight and systolic blood pressure in Asian population with type 2 diabetes from China, South Korea and India: a week, randomized, double-blind, active control trial.

Diabetes Obes Metab. Matsuzawa Y, Funahashi T, Kihara S, Shimomura I: Adiponectin and metabolic syndrome. It's cute I think plus guys like short girls.

Ahh, reminds me of one of my friends when I was He hated himself that he was short. Always talked about killing me just so he could he have my legs.

Hell naw lol. Little women, huh? That1tallguy I know the common question as to why hehe Well ni guys never set eyes on me in high school, or college or even at workplaces, no guys approached me or pursue me either but also i was shy in my high school years college.

That1tallguy never when was younger I was way too shy to do it and not only that but also I was not like a kind of girl who were after boys I mean like I was intersted in h aving a boyfriend in school anyway.

That1tallguy I agree. The second of terrible timed erections was like the entirety of morning classes for all of junior high.

Growth Spurt. Vote A. Vote B. Vote C. Mood swings. Vote D. Vote E. Select age and gender to cast your vote:.

Your age Girl Guy Please select your age. Share Facebook. What was the worst part about puberty for you? Add Opinion. I voted D, mood swings. I wasn't really that moody as a teen, I just picked D because it fits the best I guess.

I had some pretty deep insecurities that definitely affected the way I behaved. Like I would overcompensate and pretend I didn't have any insecurities.

I was extremely shy and constantly thinking of what everyone else thought of me, and I tried to battle my shyness by pushing myself to pretend I was bubbly and outgoing, which was really exhausting.

During my teens I also had severe issues with headaches, which I think might have been because of hormones and growing.

There were also times I felt particularly angsty, but most of the time that was due to me being bullied and feeling left out.

I never had any of that No mood swings Iwearyouwell Xper 2. Finding a place to have a private moment to relieve some of the tension without getting caught.

My mom did her best to keep me from chasing girls in the beginning till I got a better understanding of what was happening to me. She didn't want me to turn that loose on any poor young girl and she didn't want me to lose my mind trying to turn it loose on some poor young girl.

Thank you Mom you have no idea because I never told you how much that helped me. Mostly because it didn't seem like it at the time. I thought the best Sometimes I wished they were not there so I could just go on living life without heartbreak.

Scroll Down to Read Other Opinions What's Your Opinion? Sign Up Now! Sort Girls First Guys First.

Margillard Xper 6. The worst part was walking around all day with a perpetual hard, it was really hard to concentrate in class as the girls were hot AF, precocius and liked cock teasing.

I remember during co-ed gym class on the trampoline, a female class mate said to me that all the girls wanted to be my partner bouncing up ad down on the trampoline, watching my dick flail about in my gym shorts.

Hair growth. Not just facial hair, but chest and armpits too. I figured out rather quickly that I needed to shave at least every second day as the hair didn't even have the decency to grow evenly.

Had I let it grow it would have probably evened out decently, but I never liked the bearded look on me, so shaving was my only option, if I wanted to look presentable.

This regimen also resulted in a significant reduction in body weight and waist circumference, suggesting that the addition liraglutide to insulin treatment in obese patients with T2D maybe a more effective option than increasing the insulin dose alone.

Larger randomized, prospective studies are required to define the best practices for combination therapy with insulin and liraglutide and to evaluate its long-term cardiovascular effects.

AEs: Adverse events; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMI: Body mass index; CVD: Cardiovascular disease; FBG: Fasting blood glucose; GLP Glucagon-like peptide-1; HbA1c: Glycosylated hemoglobin; LEAD: Liraglutide Effect and Action in Diabetes; OAD: Oral antidiabetic drugs; P2BG: 2 hour postprandial blood glucose; T2D: Type 2 diabetes.

Li CJ and Yu P acquired and analyzed data, and wrote the manuscript. Yu DM conceived study, analyzed data and reviewed the manuscript. Li J, Zhang QM, Lv L, Chen R and Lv CF acquired and researched data.

All authors read and approved the final manuscript. We acknowledge the assistance of investigators and all subjects for participants in this study.

This work was supported by the National Nature Science Foundation of China No. National Center for Biotechnology Information , U.

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Journal List Cardiovasc Diabetol v. Cardiovasc Diabetol. Published online Nov PMCID: PMC Chun-jun Li , 1 Jing Li , 1 Qiu-mei Zhang , 1 Lin Lv , 1 Rui Chen , 1 Chun-feng Lv , 1 Pei Yu , 1 and De-min Yu 1.

Author information Article notes Copyright and License information Disclaimer. Corresponding author. Chun-jun Li: moc. Received Sep 5; Accepted Oct This article has been cited by other articles in PMC.

Abstract Objective To assess the efficacy and safety of adding liraglutide to established insulin therapy in poorly controlled Chinese subjects with type 2 diabetes and abdominal obesity compared with increasing insulin dose.

Methods A week, randomized, parallel-group study was carried out. Results At the end of study, the mean reduction in HbA 1c between the liraglutide-added group and the insulin-increasing group was not significantly different 1.

Conclusions Addition of liraglutide to abdominally obese, insulin-treated patients led to improvement in glycemic control similar to that achieved by increasing insulin dosage, but with a lower daily dose of insulin and fewer hypoglycemic events.

Keywords: Liraglutide, Abdominal obesity, Insulin therapy, Weight reduction. Introduction The prevalence of obesity and diabetes has rapidly increased worldwide Western and Asian countries [ 1 , 2 ].

Materials and methods Subjects This study was undertaken in the out-patient setting of the Metabolic Disease Hospital of Tianjin Medical University between October and May Study design This was a parallel-group, open-label, randomized clinical trial over a week observation period.

Clinical measurements Clinical parameters evaluated at baseline and at 3 months included HbA1c, total daily insulin dose, total-triglyceride TG , total-cholesterol, LDL-cholesterol and HDL-cholesterol.

Results Baseline clinical characteristics A total of 90 patients entered the trial and 84 patients Table 1 Characteristics of the patients at baseline.

Open in a separate window. Glycemic control and reduction of diabetes treatment Over the week treatment period, mean values of HbA 1c , FBG and P2BG were significantly reduced in both treatment groups.

Table 2 Changes of variables related with glucose metabolism after 12 weeks. Body weight and waist circumference Body weight, waist circumference and BMI were significantly decreased from baseline to 12 weeks in the liraglutide-added group, the mean reductions in body weight, waist circumference and BMI were 5.

Figure 1. Figure 2. Hypoglycemia No severe hypoglycemia was reported in the liraglutide-added group, while two patients in the insulin-increasing group reported severe hypoglycemia.

Adverse events The incidence of adverse events was higher in the liraglutide-added group than in the insulin-increasing group Discussion Compared with increasing the insulin dose therapy, the present study demonstrated the beneficial effects of adding the long-acting GLP-1 analog liraglutide to established insulin therapy, which resulted in a significant improvement in glycemic control, reduction in insulin requirement, lower incidence of hypoglycemia events and weight loss in the Chinese patients with poorly controlled T2D and abdominal obesity.

Conclusions In conclusion, adding liraglutide to insulin therapy provides a better chance of achieving good glycemic control with a lower daily insulin dose and fewer hypoglycemic events compared to increasing insulin dose.

Abbreviations AEs: Adverse events; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMI: Body mass index; CVD: Cardiovascular disease; FBG: Fasting blood glucose; GLP Glucagon-like peptide-1; HbA1c: Glycosylated hemoglobin; LEAD: Liraglutide Effect and Action in Diabetes; OAD: Oral antidiabetic drugs; P2BG: 2 hour postprandial blood glucose; T2D: Type 2 diabetes.

Competing interests The authors declare that they have no conflicts of interest. Acknowledgements We acknowledge the assistance of investigators and all subjects for participants in this study.

References Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world-a growing challenge.

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